Gu lab - publications

Publications

2025

  1. C. Chen†, Y. Gu†, J. Rufo, J. Zhang, K. Yang, Y. Chen, L.P. Lee, and T.J. Huang, “Acoustofluidic spin control for 3D particle manipulation in droplets”. Science Advances, Vol. 11, No.20, pp. eadx0269, 2025. († contributed equally to this work).
  2. A. Tehrani, S. Schoen, I. Candel, Y. Gu, P. Guo, K. Thomenius, T.T. Pierce, M. Wang, R. Tadross, M. Washburn, H. Rivaz, A. Samir, “Combining Deep Data-driven and Physics-inspired Learning for Shear Wave Speed Estimation in Ultrasound Elastography”. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 72, No. 6, pp. 806-816, 2025.

2024

  1. J. Xia, Z. Wang, R. Becker, F. Li, S. Yang, J. Rufo, S.P. Zhang, C. Chen, Y. Gu, R. Zhong, P. Lee, D. Wong, L.P. Lee, and T.J. Huang, “Super-resolution virus isolation by Bessel beam excitation separation technology: BEST”, ACS nano, Vol. 18, No. 33, pp. 22596-22607, 2024.
  2. M. Wu, Z. Ma, X. Xu, B. Lu, Y. Gu, J. Yoon, J. Xia, Z. Ma, N. Upreti, I.J. Anwar, S.J. Knechtle, E. Chambers, J. Kwun, L.P. Lee, T.J. Huang, “Acoustofluidic-based therapeutic apheresis system”, Nature Communications, Vol. 15, No. 1, pp. 6854, 2024.
  3. Z. Ma, J. Xia, N. Upreti, E. David, J. Rufo, Y. Gu, K. Yang, S. Yang, X. Xu, J. Kwun, E. Chambers, T.J. Huang, “An acoustofluidic device for the automated separation of platelet-reduced plasma from whole blood”, Microsystems & Nanoengineering, Vol. 10, No. 1, pp. 83, 2024.
  4. T. Naquin, A. Canning, Y. Gu, J. Chen, C. Naquin, J. Xia, B. Lu, S. Yang, A. Koroza, K. Lin, H. Wang, W. Jeck, L.P. Lee, T.J. Huang, “Acoustic separation and concentration of exosomes for nucleotide detection: ASCENDx”, Science Advances, Vol. 10, No. 10, eadm8597, 2024.
  5. J. Rufo, P. Zhang, Z. Wang, Y. Gu, K. Yang, C. Chen, R. Zhong, K. Jin, J. Wu, Y. Ouyang, Y. Sadovsky, L.P. Lee, T.J. Huang, “High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT”, Microsystems & Nanoengineering, Vol. 10, No. 1, pp. 1, 2024.

2023

  1. Y. Gu*, V. Kumar, E.G.S.K. Dayavansha, S. Schoen, E. Feleppa, R. Tadross, M.H. Wang, M.J. Washburn, K. Thomenius, A.E. Samir, “Acoustic diffraction-resistant adaptive profile technology (ADAPT) for elasticity imaging”, Science Advances, Vol. 9, No. 44, eadi6129, 2023. (*Corresponding Author, highlighted by 4 News Media)
  2. A. Ozturk, V. Kumar, T. Pierce, Q. Li, M. Baikpour, I. Rosado-Mendez, M. Wang, P. Guo, S. Schoen, Y. Gu, E.G.S.K. Dayavansha, J. Grajo, A. Samir, “The Future is Beyond Bright: The Evolving Role of Quantitative Ultrasound for Fatty Liver Disease”, Vol. 309, No. 2, e223146, Radiology, 2023.
  3. S. Schoen, V. Kumar, Y. Gu, E.G.S.K. Dayavansha, R. Tadross, M. Washburn, K. Thomenius, A. Samir, “Efficient Aberration Correction via Optimal Bulk Speed of Sound Compensation”, arXiv preprint arXiv:2303.02018, 2023.

2022

  1. J. Zhang, C. Chen, R. Becker, J. Rufo, S. Yang, J. Mai, P. Zhang, Y. Gu, Z. Wang, Z. Ma, J. Xia, N. Hao, Z. Tian, D. T. W. Wong, Y. Sadovsky, L. P. Lee, T. J. Huang, “A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER)”, Science Advances, Vol. 8, No. 47, eade0640, 2022.
  2. Z. Wang, J. Rich, N. Hao, Y. Gu, C. Chen, S. Yang, P. Zhang, T. J. Huang, “Acoustofluidics for simultaneous nanoparticle-based drug loading and exosome encapsulation”, Microsystems & Nanoengineering, Vol. 8, No. 1, pp. 1-11, 2022.

2021

  1. P. Zhang, J. Rufo, C. Chen, J. Xia, Z. Tian, L. Zhang, N. Hao, Z. Zhong, Y. Gu, K. Chakrabarty, and T. J. Huang, “Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials”, Nature Communications, Vol. 12, No. 1, pp. 1-10, 2021. (highlighted by 13 News Media)
  2. C. Chen, Y. Gu, J. Philippe, P. Zhang, H. Bachman, J. Zhang, J. Mai, J. Rufo, J. Rawls, E. Davis, N. Katsanis, and T. J. Huang, “Acoustofluidic rotational tweezing enables high-speed contactless morphological phenotyping of zebrafish larvae”, Nature Communications, Vol. 12, pp. 1-13, 2021. 
  3. H. Zhu, P. Zhang, Z. Zhong, J. Xia, J. Rich, J. Mai, X. Su, Z. Tian, H. Bachman, J. Rufo, Y. Gu, P. Kang, K. Chakrabarty, T. P. Witelski, and T. J. Huang, “Acoustohydrodynamic tweezers via spatial arrangement of streaming vortices”, Science Advances, Vol. 7, No. 2, eabc7885, 2021. (highlighted by Nature)
  4. Y. Gu, C. Chen, Z. Mao, H. Bachman, R. Becker, J. Rufo, Z. Wang, P. Zhang, J. Mai, S. Yang, J.   Zhang, S. Zhao, Y. Ouyang, D. T. W. Wong, Y. Sadovsky, and T. J. Huang, “Acoustofluidic centrifuge for nanoparticle enrichment and separation”, Science Advances, Vol. 7, No. 1, eabc0467, 2021. (highlighted by 16 News Media)

2020

  1. Z. Tian, Z. Wang, P. Zhang, T. D. Naquin, J. Mai, Y. Wu, S. Yang, Y. Gu, H. Bachman, Y. Liang, Z. Yu, and T. J. Huang, “Generating multifunctional acoustic tweezers in petri dishes for contactless, precise manipulation of bioparticles”, Science Advances, Vol. 6, No. 37, eabb0494, 2020. 
  2. P. Zhang, C. Chen, X. Su, J. Mai, Y. Gu, Z. Tian, H. Zhu, Z. Zhong, H. Fu, S. Yang, K. Chakrabarty, and T. J. Huang, “Acoustic streaming vortices enable contactless, digital control of droplets”, Science Advances, Vol 6, No. 24, eaba0606, 2020. (highlighted as News Report by 7 News Media)
  3. Y. Gu, C. Chen, J. Rufo, C. Shen, Z. Wang, P. H. Huang, H. Fu, P. Zhang, S. A. Cummer, Z. Tian, and T. J. Huang, “Acoustofluidic holography for micro- to nano- scale particle manipulation”, ACS Nano, Vol. 14, pp. 14635-14645, 2020. 
  4. S. Zhao, M. Wu, S. Yang, Y. Wu, Y. Gu, C. Chen, J. Ye, Z. Xie, Z. Tian, H. Bachman, P. H. Huang, J. Xia, S. P. Zhang, H. Zhang, and T. J. Huang, A disposable acoustofluidic chip for nano/micro particle separation using unidirectional acoustic transducers, Lab on a Chip, Vol 20, pp. 1298-1308, 2020.
  5. H. Bachman, Y. Gu, J. Rufo, S. Yang, Z. Tian, P. H. Huang, L. Yu, and T. J. Huang, “Low-frequency flexural wave based microparticle manipulation”, Lab on a Chip, Vol. 20, pp. 1281-1289, 2020. 

2019

  1. Z. Tian, S. Yang, P. H. Huang, Z. Wang, P. Zhang, Y. Gu, H. Bachman, C. Chen, M. Wu, Y. Xie and T. J. Huang, “Wavenumber-spiral acoustic tweezers for dynamic and reconfigurable manipulation of particles and cells”, Science Advances, Vol. 5, No. 5, eaau6062, 2019. 
  2. Z. Tian, C. Shen, J. Li, E. Reit, Y. Gu, H. Fu, S. A. Cummer, T. J. Huang, “Programmable Acoustic Metasurfaces”, Advanced Functional Materials, Vol. 29, pp. 1808489, 2019.
  3. P. Zhang, C. Chen, F. Guo, J. Philippec, Y. Gu, Z. Tian, H. Bachman, L. Ren, S. Yang, Z. Zhong, P. H. Huang, N. Katsanis, K. Chakrabarty, and T. J. Huang, “Contactless, programmable acoustofluidic manipulation of objects on water”, Lab on a Chip, Vol. 19, pp. 3397-3404, 2019. 
  4. S. Zhao, W. He, Z. Ma, P. Liu, P. H. Huang, H. Bachman, L. Wang, S. Yang, Z. Tian, Z. Wang, Y. Gu, Z. Xie, and T. J. Huang, On-Chip stool liquefaction via acoustofluidics, Lab on a Chip, Vol. 19, pp. 941-947, 2019. (featured as front cover image)
  5. Y. Gu, C. Chen, Z. Wang, P. H. Huang, H. Fu, L. Wang, M. Wu, Y. Chen, T. Gao, J. Gong, J. Kwun, G. M. Arepally, and T. J. Huang, “Plastic-based acoustofluidic devices for high-throughput, biocompatible platelet separation”, Lab on a Chip, Vol. 19, pp. 394-402, 2019. (featured as front cover image) 

2018

  1. A. Ozcelik, J. Rufo, F. Guo, Y. Gu, P. Li, J. Lata, and T. J. Huang, “Acoustic tweezers for the life sciences”, Nature Methods, Vol. 15, pp. 1021-1028, 2018.
  2. C. Chen, S. P. Zhang, Z. Mao, N. Nama, Y. Gu, P. H. Huang, Y. Jing, X. Guo, F. Costanzo and T. J. Huang, “Three-dimensional numerical simulation and experimental investigation of boundary-driven streaming in surface acoustic wave microfluidics”, Lab on a Chip, Vol. 18, pp. 3645-3654, 2018.

2017

  1. S. Liu, J. Wu, Y. Gu, X. Guo, J. Tu, D. Xu, and D. Zhang, “Ambient pressure evaluation through sub-harmonic response of chirp-sonicated microbubbles”, Ultrasound in medicine & biology, Vol. 43, pp. 332-340, 2017.

2016

  1. C. Chen, Y. Gu, J. Tu, X. Guo, D. Zhang, “Microbubble oscillating in a microvessel filled with viscous fluid: A finite element modeling study”, Ultrasonics, Vol. 66, pp. 54-64, 2016.
  2. Y. Gu, C. Chen, J. Tu, X. Guo, H. Wu, and D. Zhang, “Harmonic responses and cavitation activity of encapsulated microbubbles coupled with magnetic nanoparticles”, Ultrasonics Sonochemistry, Vol. 29, pp. 309-316, 2016.